There are a few key fantasy contributors that have had a number of injury question marks surrounding their playing status leading up to Week 5 of the 2012 NFL season. Here’s a little bit about these players and what you should consider.

Mario Manningham, the Giants wide receiver who suffered a concussion in last week's game against the St. Louis Rams probably won't play this week against the Philadelphia Eagles.

Manningham didnt practice on Friday and is currently listed as Doubtful for the Giants this weekend. And with the way the NFL treats concussions, a player who isnt cleared to practice on Friday, probably won't miraculously recover in two days to put his brain in danger on the football field.